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Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 157-175 doi: 10.1007/s11684-021-0884-z

Abstract: Therefore, early diagnosis of cancer is indispensable in the timely prevention and effective treatmentExosome has recently become an attractive cancer biomarker in noninvasive early diagnosis because ofdiagnosis of cancer.diagnosis of cancer were evaluated.diagnosis of cancer were discussed.

Keywords： biosensor     exosome     cancer diagnosis    

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Early diagnosis and therapeutic choice of

Jing LI, Ying FU, Ji-Yao WANG, Chuan-Tao TU, Xi-Zhong SHEN, Lei LI, Wei JIANG

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 308-316 doi: 10.1007/s11684-010-0103-9

Abstract: Our study aims to achieve an early pathogenic diagnosis and rational therapy modality for liver abscessstrong association with diabetes, milder clinical symptoms, and gas-forming nature in CT images makes earlypathogenic diagnosis of KLA possible.

Keywords： liver abscess     Klebsiella pneumoniae     computed tomography     therapy    

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Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader–Willi syndrome

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 946-956 doi: 10.1007/s11684-022-0962-x

Abstract: uncover RBC deformation in children with PWS, and this may constitute an auxiliary indicator of PWS in early

Keywords： Prader–Willi syndrome     early diagnosis     erythrocyte deformation     membrane skeleton     membrane lipid    

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A reignited debate over the cell(s) of origin for glioblastoma and its clinical implications

Xiaolin Fan, Yanzhen Xiong, Yuan Wang

Frontiers of Medicine 2019, Volume 13, Issue 5,   Pages 531-539 doi: 10.1007/s11684-019-0700-1

Abstract: remains poor, with a median survival of 14−16 months. 90% of GBMs are primary GBMs that are full-blown at diagnosisprogress and debate in the field, explore the clinical implications, and propose future directions toward earlydiagnosis and preventive treatment of GBMs.

Keywords： glioblastoma     cell(s) of origin     neural stem cells     oligodendrocyte precursor cells     subventricular zone     earlydiagnosis    

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Effects of exercise therapy on bone mineral density in early postmenopausal women: a controlled trial

Shilin DENG MD ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 323-329 doi: 10.1007/s11684-009-0061-2

Abstract: Further, the exact dose-response relationship of exercise and bone mass in early postmenopause is not

Keywords： early postmenopausal women     bone mineral density     exercise     effects    

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RESEARCH AND APPLICATION OF CROP PEST MONITORING AND EARLY WARNING TECHNOLOGY IN CHINA

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1,   Pages 19-36 doi: 10.15302/J-FASE-2021411

Abstract: Nevertheless, the use of science and technology in monitoring and early warning of major crop pests providesThis review summarizes the most fundamental information on pest monitoring and early warning in Chinaapplication, Chinese laws and regulations related to plant protection, and the National Monitoring and Early

Keywords： China / law / early warning system and national crop pest monitoring / pest management / regulation and    

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Expression of inducible nitric oxide synthase in trophoblasts and deciduas in early medical abortion

Geqing XIA, Chaoying WU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 216-219 doi: 10.1007/s11684-009-0028-3

Abstract: was to investigate the expression of inducible nitric oxide synthase in trophoblasts and deciduas in earlyrelationship of medical abortion through mifepristone and inducible nitric oxide synthase (iNOS) in early

Keywords： mifepristone     inducible nitric oxide synthase     early pregnancy     placental immunity    

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Role of chemerin/CMKLR1 in the maintenance of early pregnancy

Xuezhou Yang, Junning Yao, Qipeng Wei, Jinhai Ye, Xiaofang Yin, Xiaozhen Quan, Yanli Lan, Hui Xing

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 525-532 doi: 10.1007/s11684-017-0577-9

Abstract: explore the effects of chemerin and its receptor chemokine-like receptor 1 (CMKLR1) on the maintenance of earlyThe expression levels of chemerin and CMKLR1 in the decidua tissues of 20 early normal pregnant womenand 20 early spontaneous abortion women were examined by Western blot and real-time polymerase chainWe found that the expression level of chemerin in women who had experienced early spontaneous abortionwas lower than in those who had experienced normal early pregnancy (P<0.01); conversely, CMKLR1

Keywords： chemerin     CMKLR1     early abortion    

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Weak characteristic information extraction from early fault of wind turbine generator gearbox

Xiaoli XU, Xiuli LIU

Frontiers of Mechanical Engineering 2017, Volume 12, Issue 3,   Pages 357-366 doi: 10.1007/s11465-017-0423-4

Abstract:

Given the weak early degradation characteristic information during early fault evolution in gearboxmethod can significantly weaken signal noise, effectively extract the weak characteristic information of earlyfault, and facilitate the early fault warning and dynamic predictive maintenance.

Keywords： µ-singular value decomposition     local mean decomposition     weak characteristic information extraction     early    

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Early-onset diabetes: an epidemic in China

Jiemin Pan, Weiping Jia

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 624-633 doi: 10.1007/s11684-018-0669-1

Abstract:

Although type 2 diabetes is a disease often associated with aging, the global prevalence of early-onsetMany studies have found that individuals with early-onset type 2 diabetes were at higher risk of developingIndividuals with early-onset diabetes are usually unwilling to visit hospital and have more confidencefocused on the treatment and prevention of complications in specific population of individuals with early-onsetMore data are definitely required to establish a reasonable risk model to screen for early-onset diabetes

Keywords： diabetes     early-onset     diabetes complications    

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Laboratory diagnosis for malaria in the elimination phase in China: efforts and challenges

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 10-16 doi: 10.1007/s11684-021-0889-7

Abstract: The prompt and precise diagnosis of symptomatic and asymptomatic carriers of Plasmodium parasitesof the China Malaria Elimination Action Plan in 2010, China has formulated clear goals for malaria diagnosisVarious external quality assessments were implemented, and a national malaria diagnosis reference laboratorynetwork was established to strengthen the quality assurance in malaria diagnosis.This review summarizes the lessons about malaria diagnosis in the elimination phase, primarily including

Keywords： malaria     laboratory diagnosis     quality control     malaria elimination     China    

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The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 391-395 doi: 10.1007/s11684-008-0075-1

Abstract: To study the effects of early signal substances induced by heat stress in brains of Kunming mice, six-month-old

Keywords： calcitonin gene-related     subsequent ischemia/reperfusion     computer     cerebrum     CGRP excretion    

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Effects of DNA damage on oocyte meiotic maturation and early embryonic development

Shen YIN,Junyu MA,Wei SHEN

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3,   Pages 185-190 doi: 10.15302/J-FASE-2014035

Abstract: DNA damage is one of the most common threats to meiotic cells. It has the potential to induce infertility and genetic abnormalities that may be passed to the embryo. Here, we reviewed exogenous factors which could induce DNA damage. Specially, we addressed the different effects of DNA damage on mouse oocytes and embryonic development. Complex DNA damage, double-strand breaks, represents a more difficult repair process and involves various repair pathways. Understanding the mechanisms involved in DNA damage responses may improve therapeutic strategies for ovarian cancer and fertility preservation.

Keywords： DNA damage     double-strand breaks (DSBs)     oocyte     embryo    

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Tomographic diagnosis of defects in hydraulic concrete structure

ZHAO Mingjie, XU Xibin

Frontiers of Structural and Civil Engineering 2008, Volume 2, Issue 3,   Pages 226-232 doi: 10.1007/s11709-008-0027-5

Abstract: The experimental results indicate that the result of the tomographic diagnosis of a single defect isDefects with the orientation perpendicular to the direction of the diagnosis may have higher precision

Keywords： satisfactory     processing     orientation     tomographic diagnosis     orientation perpendicular    

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convolutional tree-inspired network: a decision-tree-structured neural network for hierarchical fault diagnosis

Frontiers of Mechanical Engineering 2021, Volume 16, Issue 4,   Pages 814-828 doi: 10.1007/s11465-021-0650-6

Abstract: The fault diagnosis of bearings is crucial in ensuring the reliability of rotating machinery.However, the inexplicability and low generalization ability of fault diagnosis models still bar themneural network, that is, the deep convolutional tree-inspired network (DCTN), for the hierarchical fault diagnosisadvantages in 1) the hierarchical structure that can support more accuracy and comprehensive fault diagnosisThe multiclass fault diagnosis case and cross-severity fault diagnosis case are executed on a multicondition

Keywords： bearing     cross-severity fault diagnosis     hierarchical fault diagnosis     convolutional neural network    

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Title Author Date Type Operation

Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Journal Article

Early diagnosis and therapeutic choice of

Jing LI, Ying FU, Ji-Yao WANG, Chuan-Tao TU, Xi-Zhong SHEN, Lei LI, Wei JIANG

Journal Article

Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader–Willi syndrome

Journal Article

A reignited debate over the cell(s) of origin for glioblastoma and its clinical implications

Xiaolin Fan, Yanzhen Xiong, Yuan Wang

Journal Article

Effects of exercise therapy on bone mineral density in early postmenopausal women: a controlled trial

Shilin DENG MD ,

Journal Article

RESEARCH AND APPLICATION OF CROP PEST MONITORING AND EARLY WARNING TECHNOLOGY IN CHINA

Journal Article

Expression of inducible nitric oxide synthase in trophoblasts and deciduas in early medical abortion

Geqing XIA, Chaoying WU

Journal Article

Role of chemerin/CMKLR1 in the maintenance of early pregnancy

Xuezhou Yang, Junning Yao, Qipeng Wei, Jinhai Ye, Xiaofang Yin, Xiaozhen Quan, Yanli Lan, Hui Xing

Journal Article

Weak characteristic information extraction from early fault of wind turbine generator gearbox

Xiaoli XU, Xiuli LIU

Journal Article

Early-onset diabetes: an epidemic in China

Jiemin Pan, Weiping Jia

Journal Article

Laboratory diagnosis for malaria in the elimination phase in China: efforts and challenges

Journal Article

The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Journal Article

Effects of DNA damage on oocyte meiotic maturation and early embryonic development

Shen YIN,Junyu MA,Wei SHEN

Journal Article

Tomographic diagnosis of defects in hydraulic concrete structure

ZHAO Mingjie, XU Xibin

Journal Article

convolutional tree-inspired network: a decision-tree-structured neural network for hierarchical fault diagnosis

Journal Article